By Philip C. Burcham

This ebook presents a readable advent to trendy toxicology with a specific specialize in the mechanisms underlying the induction of toxicity via overseas elements. due to the fact that bioactivation is crucial to many poisonous syndromes, specified curiosity is dedicated to chemical compounds that suffer conversion to poisonous metabolites that set off poisonous results as diversified as melanoma, start defects and organ damage. The molecular outcomes accompanying harm to mobile DNA and proteins is explored including the relevance of toxicological paradigms to human ailments because of alcohol and tobacco. The self-discipline of toxicology has constructed swiftly because the thalidomide catastrophe within the 1960’s as scientists around the world search to appreciate the opposed healthiness results of human medications, environmental pollution, customer chemical substances and commercial reagents. An advent to Toxicology is meant to complement the prompt interpreting record of undergraduate and graduate courses in toxicology and pharmacology as an stress-free, obtainable primer with illustrations that “unpack” the strategies being mentioned within the textual content. ​

 

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An Introduction to Toxicology by Philip C. Burcham


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